George Babcock, B.S., M.S. Ph.D.

Research interests

Research in the area of immunology especially as it relates to burns, infectious diseases, toxicology and wound healing.  Development and testing of new antimicrobials and delivery systems.  The role of neutrophils, macrophages and microvesicles in host defense; immunotherapy for infections; nutritional manipulation of immune response. The use of flow and image cytometry to measure biological responses, genetic control of immune system and mechanisms of action of biological response modifiers.

Biography

Dr. Babcock has a background in immunology and obtained his PhD and postdoctoral training in this area from the University of Nebraska Medical Center and the University of North Carolina-Chapel Hill, respectively. He currently performs research in the area of trauma/sepsis, wound healing, toxicology as it relates to the immune system and also directs the flow cytometry core facility. He has served on NIH and DOD study sections and is currently the chair of the Military Infectious Diseases Research Program (MIDRP) study section.  Dr. Babcock is chair of the University of Cincinnati IACUC which is responsible for the animals at the three main campuses and two branch campuses of UC, plus at the Shriners Hospitals for Children-Cincinnati. In the role of IACUC chair, he reports to the associate vice president for Research Integrity, who serves as the institutional official. Additionally, he is on the institutional biosafety committee and interfaces with the Radiation Safety Department, the Human Health and Safety Department, and the Office of Research Compliance and Regulatory Affairs on issues relating to animals and animal workers.

Education and training

B.S. Muskingum University, New Concord, Ohio (Biology)

M.S. North Dakota State University, Fargo, North Dakota (Bacteriology)

Ph.D. University of Nebraska Medical Center, Omaha, Nebraska (Medical Microbiology and Immunology)

Postdoctoral Training:  Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, Laboratory of Dr. Geoffrey Haughton

Publications 

Hexley P and G. Babcock. The technology revolution at the limits of detection.  SOJ Immunol. 1(1) 3: ejournal.DOI: 10.15226. 2013.

Hexley P., C. T. Robinson, K. P. Rismiller, G. F. Babcock.   Protocol standardization of Microvesicle Quantification by  Flow Cytometry Reveals a Correlation to Healthy Donor Total Body Weight.   Exosomes and Microvesicles. Epub March  21.  DOI: 0.5772/58527. 2014.

Yamaguchi R,  A. Osterburg, S.H. Hyon, C.T. Robinson, G. F. Babcock. The effects of (-) epigallocatechin-3-gallate (EGCG) on wound closure in mice.  Surg. Res. 1:1-8. DOI: http://dx.doi.org/SROJ/SROJ-1-101. 2014.

Tetens-Woodring, J. G.F. Babcock, and M. Jonnalagadda. Referencing an approved protocol in an amendment: more or less administrative burden. Lab Animal 45: doi:10.1038/laban.l066. 2016.

Grants

Departmental of Defense Grant W81XWH-15-2-0065. Efficacy and Safety of A BLOCKS against Gram positive and Gram negative bacteria in deep tissue contamination/infection with a foreign body in a rat model. PI, 10-16 to 12-17.

SHCC-87100-Development/Testing of Negative Pressure Capillary Dressings to Improve Wound Healing. PI, 1-1-17 to 12-31-18.

Contact

George Babcock, B.S., M.S. Ph.D.
Professor Emeritus
Dept. of Surgery, University of Cincinnati
Assistant Director of Research
SHCC
[email protected]

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